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1

Can we increase the chance of sphincter saving surgery in rectal cancer with neoadjuvant treatments: Lessons from a systematic review of recent randomized trials

Jean-Pierre Gerard, Yousri Rostom, Jocelyn Gal, Daniel Benchimol, Cécile Ortholan, Carlo Aschele, Jean-Michel Hannoun Levi

Journal:

Critical Reviews in Oncology/Hematology

Year:

2012

Language:

english

File:

PDF, 216 KB

english, 2012

2

Alternating bolus and continuous infusion 5-fluorouracil: a strategy to overcome resistance to this fluoropyrimidine in advanced colorectal cancer patients

A. Guglielmi, C. Aschele, F. Grossi, L. Tixi, A. Sobrero

Journal:

Year:

1996

Language:

english

File:

PDF, 432 KB

english, 1996

3

Complications, continence and quality of life after an intensive preoperative radio-chemotherapy regimen for locally advanced rectal cancer: analysis of a phase I–II study

S. Pucciarelli, E. Urso, S. Serpentini, P. Toppan, G. L. De Salvo, G. Fabris, M. L. Friso, C. Aschele, A. Bruttocao, M. Lise

Journal:

Annals of Surgical Oncology

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

4

5-Fluorouracil and Weekly Oxaliplatin Combined with Radiotherapy for Locally Advanced Rectal Cancer: Surgical Complications and Long-term Results

Salvatore Pucciarelli, Emanuele Urso, Gian Luca DeSalvo, Carlo Aschele, Maria Luisa Friso, Massimo Rugge, Paola Toppan, Andrea Bruttocao, Giuliano Fabris, Benito Ferraro, Sara Lonardi, Mauro Frego, Cr

Journal:

Archives of Medical Research

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

5

Radiochemotherapy in rectal cancer: the role of oxaliplatin

J.-P. Gerard, R. Glynne-Jones, W. Blackstock, C. Aschele, C. Van De Velde

Journal:

Colorectal Disease

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

6

Ondansetron for the control of dacarbazine-induced emesis

E. Campora, S. Chiara, C. Aschele

Journal:

European Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 261 KB

english, 1995

7

305 Circumvention of resistance to 5-fluorouracil by schedule-oriented biochemical modulation in advanced colon cancer patients

A. Sobrero, C. Aschele, A. Guglielmi, A. Mori, L. Tixi, E. Bolli, F. Grossi

Journal:

European Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 296 KB

english, 1995

8

Chemotherapy for operable and advanced colorectal cancer

Carlo Aschele, Francesca Bergamo, Sara Lonardi

Journal:

Cancer Treatment Reviews

Year:

2009

Language:

english

File:

PDF, 182 KB

english, 2009

9

Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma

D.I Jodrell, T.R.J Evans, W Steward, D Cameron, J Prendiville, C Aschele, C Noberasco, M Lind, J Carmichael, N Dobbs, G Camboni, B Gatti, F De Braud

Journal:

European Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

10

Complications, functional outcome and quality of life after intensive preoperative chemoradiotherapy for rectal cancer

E. Urso, S. Serpentini, S. Pucciarelli, G.L. De Salvo, M.L. Friso, G. Fabris, S. Lonardi, B. Ferraro, A. Bruttocao, C. Aschele, D. Nitti

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2006

Language:

english

File:

PDF, 155 KB

english, 2006

11

A phase I study of weekly oxaliplatin (OXA), 5-fluorouracil (5-FU) continuous infusion and preoperative radiotherapy in locally advanced rectal cancer

C. Aschele, M. Friso, S. Pucciarelli, G. Babris, B. Martella, G. Da Dalt, E. Urso, D. Neri, O. Lora, S. Monfardini

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 350 KB

english, 2001

12

A phase I study of weekly oxaliplatin (OXA) + continous infusion (CI) fluorouracil (FU) in patients with advanced colorectal cancer(CCR)

A. Aschele, S. Lonardi, L. Sartor, A. Perin, V. Chiarion Sileni, G. Artioli, S. Monfardini

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

13

Thymidylate synthase (TS) protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil (5FU)

S. Cascinu, C. Aschele, S. Barni, D. Debernardis, C. Baldo, G. Tunesi, V. Catalano, P. Giordani, A.M. Baldelli, G. Catalano

Journal:

European Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 119 KB

english, 1999

14

Thymidylate Synthase expression as a predictor of clinical response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer

C. Aschele, S. Lonardi, S. Monfardini

Journal:

Cancer Treatment Reviews

Year:

2002

Language:

english

File:

PDF, 254 KB

english, 2002

15

238 Gemcitabine (GEM) as salvage treatment in patients (pts) with advanced colorectal cancer (CRC) progressing after treatment with 5-fluorouracil (FU), irinotecan (lrl) and oxaliplatin (oxa)

C. Aschele, S. Lonardi, S. Garrè, C. Caroti, M. D'Amico, L.M. Pasetto, M. Stefani, P. Pronzato, L. Gallo, S. Monfardini

Journal:

European Journal of Cancer Supplements

Year:

2003

Language:

english

File:

PDF, 169 KB

english, 2003

16

284 DCC protein expression in colorectal cancer (CRC) metastases and lack of response to biochemically-modulated 5-fluorouracil (FU) among patients (pts) with low level of thymidylate synthase (TS) protein expression

S. Lonardi, S. Casazza, D. Debernardis, S. Garrè, L. Gallo, S. Monfardini, C. Aschele

Journal:

European Journal of Cancer Supplements

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003

17

5-Fluorouracil plus 5-methyltetrahydrofolate in advanced pancreatic cancer

E. Bolli, S. Saccomanno, G. Mondini, C. Aschele…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1995

Language:

english

File:

PDF, 378 KB

english, 1995

18

Phase II study of 5-fluorouracil plus leucovorin and interferon alpha 2b in advanced colorectal cancer

Sobrero, A., Nobile, M.T., Guglielmi, A., Mori, A., Aschele, C., Bolli, E., Tixi, L., Gallo, L., Parodi, G.C., Bruzzi, P., Brema, F., Rosso, R.

Journal:

European Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 409 KB

english, 1992

19

A phase II study of leucovorin (LV)-modulated continuous infusion (CI) fluorouracil (DU) + CPT-11 alternating with LV-modulated CI FU + Oxaliplatin (L-OHP) in advanced colorectal cancer (CCR): high activity and low toxicity

Aschele, A., Lonardi, S., Sartor, L., Perin, A., Koussis, B., Nicoletto, O., Monfardini, S.

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

20

6045 Safety analysis of starpan (star-02) study with panitumumab, 5-fluorouracil, oxaliplatin and concurrent radiotherapy in locally advanced rectal cancer

Fabio, F. Di, Pinto, C., Maiello, E., Pini, S., Latiano, T., Aschele, C., Garufi, C., Bochicchio, A., Tassinari, D., Martoni, A.

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

21

Liver targeting of autologous erythrocytes loaded with doxorubicin

Tonetti, Michela, Polvani, Carolina, Zocchi, Elena, Guida, Lucrezia, Benatti, Umberto, Biassoni, Paolo, Romei, Federico, Guglielmi, Alessandra, Aschele, Carlo, Sobrero, Alberto

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1991

Language:

english

File:

PDF, 275 KB

english, 1991

22

Preoperative chemoradiation for rectal cancer. Toxicity, downstaging and complications in 114 patients

Friso, M.L., Pucciarelli, S., Aschele, C., Lora, O., Loreggian, L., Fasano, C., Toppan, P., Muzzio, P.C., Sotti, G.

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 359 KB

english, 2001

23

Dacarbazine and fotemustine in advanced colorectal cancer

Tixi, L., Bolli, E., Guglielmi, A., Mori, A., Aschele, C., Nobile, M.T., Rosso, R., Sobrero, A.

Journal:

European Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 141 KB

english, 1993

24

Determinants of sensitivity and resistance to fluoropyrimidines

Aschele, C., Guglielmi, A., Maioli, D., Sobrero, A., Rosso, R., Nicolin, A.

Journal:

Pharmacological Research

Year:

1990

Language:

english

File:

PDF, 171 KB

english, 1990

25

Anal cancer: ESMO–ESSO–ESTRO clinical practice guidelines for diagnosis, treatment and follow-up

Glynne-Jones, Robert, Nilsson, Per J., Aschele, Carlo, Goh, Vicky, Peiffert, Didier, Cervantes, Andrés, Arnold, Dirk

Journal:

Radiotherapy and Oncology

Year:

2014

Language:

english

File:

PDF, 838 KB

english, 2014

26

Anal cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up

Glynne-Jones, R., Nilsson, P.J., Aschele, C., Goh, V., Peiffert, D., Cervantes, A., Arnold, D.

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2014

Language:

english

File:

PDF, 680 KB

english, 2014

27

A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer

Journal:

Annals of Oncology

Year:

2005

Language:

english

File:

PDF, 72 KB

english, 2005

28

Primary Tumor Response to Preoperative Chemoradiation With or Without Oxaliplatin in Locally Advanced Rectal Cancer: Pathologic Results of the STAR-01 Randomized Phase III Trial

Aschele, C., Cionini, L., Lonardi, S., Pinto, C., Cordio, S., Rosati, G., Artale, S., Tagliagambe, A., Ambrosini, G., Rosetti, P., Bonetti, A., Negru, M. E., Tronconi, M. C., Luppi, G., Silvano, G., C

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 233 KB

english, 2011

29

5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer

Sobrero, A, Guglielmi, A, Cirillo, M, Recaldin, E, Frassineti, G L, Aschele, C, Ravaioli, A, Testore, P, Caroti, C, Gallo, L, Pessi, M A, Cortesi, E, Turci, D, Grossi, F, Labianca, R

Journal:

British Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 64 KB

english, 2001

30

Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil

Journal:

Annals of Oncology

Year:

2002

Language:

english

File:

PDF, 277 KB

english, 2002

31

Rectal Cancer: Rectal Preservation Is an Important End Point

Gerard, J.-P., Francois, E., Freyer, G., Milano, G., Aschele, C.

Journal:

Journal of Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 66 KB

english, 2010

32

Deleted in Colon Cancer Protein Expression in Colorectal Cancer Metastases: A Major Predictor of Survival in Patients With Unresectable Metastatic Disease Receiving Palliative Fluorouracil-Based Chemotherapy

Journal:

Journal of Clinical Oncology

Year:

2004

Language:

english

File:

PDF, 483 KB

english, 2004

33

Addition of Weekly Oxaliplatin to Standard Preoperative Chemoradiation for Locally Advanced Rectal Cancer

Aschele, C., Lonardi, S.

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

34

Reply to Letter to the Editor 'Weekly oxaliplatin and pre-operative radiotherapy as a new neoadjuvant therapy for locally advanced rectal cancer', by T. Watanabe et al. (Ann Oncol 2006; 17: 1173)

Journal:

Annals of Oncology

Year:

2006

Language:

english

File:

PDF, 38 KB

english, 2006

35

Multidisciplinary treatment of rectal cancer: medical oncology

Aschele, C., Lonardi, S.

Journal:

Annals of Oncology

Year:

2007

Language:

english

File:

PDF, 166 KB

english, 2007

36

Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (StarPan/STAR-02 Study)

Pinto, C., Di Fabio, F., Maiello, E., Pini, S., Latiano, T., Aschele, C., Garufi, C., Bochicchio, A., Rosati, G., Aprile, G., Giaquinta, S., Torri, V., Bardelli, A., Gion, M., Martoni, A.

Journal:

Annals of Oncology

Year:

2011

Language:

english

File:

PDF, 160 KB

english, 2011

37

Anal cancer: ESMO-ESSO-ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Glynne-Jones, R., Nilsson, P. J., Aschele, C., Goh, V., Peiffert, D., Cervantes, A., Arnold, D.

Journal:

Annals of Oncology

Year:

2014

Language:

english

File:

PDF, 424 KB

english, 2014

38

Synergism and Lack of Cross-resistance Between Short-term and Continuous Exposure to Fluorouracil in Human Colon Adenocarcinoma Cells

Sobrero, A. F., Aschele, C., Guglielmi, A. P., Mori, A. M., Melioli, G. G., Rosso, R., Bertino, J. R.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1993

Language:

english

File:

PDF, 812 KB

english, 1993

39

Multidisciplinary treatment of rectal cancer: medical oncology

Aschele, C., Lonardi, S.

Journal:

Annals of Oncology

Year:

2007

Language:

english

File:

PDF, 191 KB

english, 2007

40

Precoagulation-assisted parenchyma-sparing laparoscopic liver surgery: rationale and surgical technique

Francone, Elisa, Muzio, Elena, D’Ambra, Luigi, Aschele, Carlo, Stefanini, Teseo, Sani, Cinzia, Falco, Emilio, Berti, Stefano

Journal:

Surgical Endoscopy

Year:

2017

Language:

english

File:

PDF, 785 KB

english, 2017

41

Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: a multicentre observational study

Barina, A., Paoli, A. De, Delrio, P., Guerrieri, M., Muratore, A., Bianco, F., Vespa, D., Asteria, C., Morpurgo, E., Restivo, A., Coco, C., Pace, U., Belluco, C., Aschele, C., Lonardi, S., Valentini,

Journal:

Techniques in Coloproctology

Year:

2017

Language:

english

File:

PDF, 646 KB

english, 2017

42

Management of metastatic colorectal cancer patients: guidelines of the Italian Medical Oncology Association (AIOM)

Salvatore, Lisa, Aprile, Giuseppe, Arnoldi, Ermenegildo, Aschele, Carlo, Carnaghi, Carlo, Cosimelli, Maurizio, Maiello, Evaristo, Normanno, Nicola, Sciallero, Stefania, Valvo, Francesca, Beretta, Gior

Journal:

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

43

Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer: a multicentric phase II study

Aschele, C, Guglielmi, A, Frassineti, GL, Milandri, C, Amadori, D, Labianca, R, Vinci, M, Tixi, L, Caroti, C, Ciferri, E, Verdi, E, Rosso, R, Sobrero, A

Journal:

British Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 1.12 MB

english, 1998

44

Current Strategies to Reduce Cisplatin Toxicity

Sobrero, A., Guglielmi, A., Aschele, C., Rosso, R.

Journal:

Journal of Chemotherapy

Year:

1990

Language:

english

File:

PDF, 988 KB

english, 1990

45

Resistance to 5-Fluorouracil and 5-Fluoro;-2’-deoxyuridine Mechanisms and Clinical Implications

Sobrero, A., Aschele, C., Guglielmi, A., Nobile, M.T., Rosso, R.

Journal:

Journal of Chemotherapy

Year:

1990

Language:

english

File:

PDF, 988 KB

english, 1990

46

Authors’ reply to “Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: potential pitfalls of a multicentre observational study”

Pucciarelli, S., Valentini, V., Aschele, C., Barina, A.

Journal:

Techniques in Coloproctology

Year:

2018

Language:

english

File:

PDF, 644 KB

english, 2018

47

Phase II Study of Preoperative Treatment with External Radiotherapy Plus Panitumumab in Low‐Risk, Locally Advanced Rectal Cancer (RaP Study/STAR‐03)

Pinto, Carmine, Di Bisceglie, Maurizio, Di Fabio, Francesca, Bochicchio, Annamaria, Latiano, Tiziana, Cordio, Stefano, Rosati, Gerardo, Aschele, Carlo, Marino, Antonella, Bergamo, Francesca, Bustreo,

Journal:

Year:

2018

Language:

english

File:

PDF, 226 KB

english, 2018

48

Primary melanoma of the bladder: Case report and review of the literature

Barillaro, Francesco, Camilli, Marco, Dessanti, Paolo, Gorji, Nader, Chiesa, Fabio, Villa, Alessandro, Pastorino, Alessandro, Aschele, Carlo, Conti, Enrico

Journal:

Archivio Italiano di Urologia e Andrologia

Year:

2018

Language:

english

File:

PDF, 479 KB

english, 2018

49

D07Phase II open-label single-arm study of pre-operative panitumumab and external pelvic radiotherapy (RTE) in locally advanced rectal cancer (LARC) patients (pts) (RaP/STAR-03 Study)

Pinto, C., Di Bisceglie, M., Di Fabio, F., Bochicchio, A.M., Latiano, T., Cordio, S., Rosati, G., Aschele, C., Marino, A., Bergamo, F., Bustreo, S., Frassineti, L., Ciardiello, F., Giaquinta, S., Bald

Journal:

Annals of Oncology

Year:

2016

File:

PDF, 67 KB

2016

50

Chemotherapy of Advanced Colorectal Cancer: Inhibition of Thymidylate Synthase

Sobrero, Alberto F., Guglielmi, Alessandra, Tempestini, Alessio, Baldo, Chiara, Aschele, Carlo

Journal:

Year:

1997

Language:

english

File:

PDF, 81 KB

english, 1997

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